BOPI 06 BR / 2025 REPERTOIRE NUMERIQUE 36 Figure 4 ________________________________________ (11) 21955 Consulter le mémoire (51) A61K 39/395 (2018.01); C07K 16/28 (2018.01); C07K 16/30 (2018.01) (21) 1202300284 - PCT/US2022/011969 (22) 11/01/2022 (30) US n° 63/135, 827 du 11/01/2021 (54) Antibodies Targeted To CD147. (72) DE LA CRUZ, Vidal Felix (US); CROCI, Alberto Murat (US) et KARLIN, Michael Joseph (US) (73) Ibex Biosciences, Inc., 320 Greene Street, CUMBERLAND, Maryland 21502 (US) (74) SPOOR & FISHER Inc. NGWAFOR & PARTNERS SARL, The House of Gideon, Golf/Bastos Quarters, Opposite The American Embassy, Entrance-Saint John Paul II Boulevard, B.P. 8211, YAOUNDE (CM). (57) Provided herein arc novel antibody sequences that bind to CD 147 and inhibit viral or parasite invasion, ecduce inflammation, and reduce cancer cell viability. The present disclosure also provides methods of using these antibodies to treat viral infection and cancer.
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